Polymorphism of stearoyl-CoA desaturase (SCD1) gene in Indonesian local cattle
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چکیده
منابع مشابه
Investigation of (Stearoyl-CoA Desaturase 1) SCD1 Gene Polymorphism in Khuzestan Buffalo Population Using PCR-RFLPMethod
Stearoyl-CoA desaturase (SCD) is a rate-limiting enzyme in the biosynthesis of monounsaturated fatty acids (MUFA). A number of studies support the hypothesis that SCD gene regulation and polymorphism may affect fatty acid composition and fat quality in meat and milk. Single nucleotide polymorphisms in the coding region of the bovine stearoyl-CoA desaturase gene have been predicted to result in ...
متن کاملinvestigation of (stearoyl-coa desaturase 1) scd1 gene polymorphism in khuzestan buffalo population using pcr-rflpmethod
stearoyl-coa desaturase (scd) is a rate-limiting enzyme in the biosynthesis of monounsaturated fatty acids (mufa). a number of studies support the hypothesis that scd gene regulation and polymorphism may affect fatty acid composition and fat quality in meat and milk. single nucleotide polymorphisms in the coding region of the bovine stearoyl-coa desaturase gene have been predicted to result in ...
متن کاملSignificant associations of stearoyl-CoA desaturase (SCD1) gene with fat deposition and composition in skeletal muscle
Gene expression studies in humans and animals have shown that elevated stearoyl-CoA desaturase (SCD1) activity is associated with increased fat accumulation and monounsaturation of saturated fatty acids in skeletal muscle. However, results of the two reported association studies in humans are inconsistent. In the present study, we annotated the bovine SCD1 gene and identified 3 single nucleotid...
متن کاملInhibition of Stearoyl-CoA Desaturase 1 (SCD1) DissociatesInsulin Resistance and Obesity From Atherosclerosis
Background—Stearoyl-CoA Desaturase 1 (SCD1) is a well-known enhancer of the metabolic syndrome. The purpose of the present study was to investigate the role of SCD1 in lipoprotein metabolism and atherosclerosis progression. Methods and Results—Antisense oligonucleotides were used to inhibit SCD1 in a mouse model of hyperlipidemia and atherosclerosis (LDLr-/-Apob100/100). In agreement with previ...
متن کاملHeterogeneity of the Stearoyl-CoA desaturase-1 (SCD1) Gene and Metabolic Risk Factors in the EPIC-Potsdam Study
BACKGROUND Stearoyl-CoA desaturase-1 (SCD1) is an enzyme involved in lipid metabolism. In mice and humans its activity has been associated with traits of the metabolic syndrome, but also with the prevention of saturated fatty acids accumulation and subsequent inflammation, whereas for liver fat content inconsistent results have been reported. Thus, variants of the gene encoding SCD1 (SCD1) coul...
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ژورنال
عنوان ژورنال: Journal of the Indonesian Tropical Animal Agriculture
سال: 2017
ISSN: 2460-6278,2087-8273
DOI: 10.14710/jitaa.42.1.1-5